ABSTRACT
Chinese materia medica (CMM) cosmetics are made of natural CMM or by adding CMM or its active ingredients into the chemical compound matrices. They are increasingly favored by consumers all over the world due to the facts that they are guided by traditional Chinese medicine (TCM) theory, as well as are green, natural, safe, and reliable. But, not all natural CMM cosmetics are absolutely safe. This paper summarizes the toxic and side effects of some raw materials in CMM cosmetics, which are classified to skin-irritation, photo-toxicity, and the accumulation of toxic like renal toxicity, liver toxicity, neurotoxicity, and so on. This review will provide the references for the proper use of natural raw materials in CMM cosmetics to ensure the safety of consumers.
ABSTRACT
Ochratoxin A (OTA) is a toxic secondary metabolite mainly produced by Aspergillus and Penicillium species, existing in a variety of foodstuffs and Chinese medicines. OTA is difficult to be detected in practice because of the characteristics such as trace amounts, toxicity, existing in complex matrices. In the numerous detection technologies, colloidal gold chromatographic techniques are highly sensitive, specific, cost-effective and user-friendly, and are being used increasingly for OTA screening. Recently, with the development of aptamer technology and its application in chromatographic technique, a newly colloidal gold aptamer chromatographic technique has been developed. This review elaborates the structures and principles of both traditional and newly colloidal gold chromatographic techniques, focuses on newly colloidal gold aptamer chromatographic technique, summarizes and compares their use in rapid detection of OTA. Finally, in order to provide a reference for better research of related work, the development trends of this novel technique are prospected.